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Selection of milestones in the genetic manipulation of P. falciparum blood stages.
|
Year |
Method |
Refs. |
|---|---|---|
|
1993 |
Transient transfection |
[7] |
|
1995 |
Stable transfection |
[8] |
|
1996 |
Gene‐targeted/HR‐based |
[177] |
|
2006 |
Bxb1 integrase‐mediated site‐specific integration |
[178] |
|
2014 |
CRISPR/Cas9 |
[179–181] |
|
2017 |
Selection‐linked integration (SLI) |
[10] |
