. 2021 Mar 11;93(8):4704–4713. doi: 10.1002/jmv.26877

Table 2.

Characteristics of subjects and cytokine levels included in the study

Characteristics	SFTS patient group (n = 100)^a	Healthy people group (n = 100)	Asymptomatic infected person group (n = 100)	p value^b	P value^c	p value^d	p value^e
IL‐6	71.39	25.32	29.80	<.001^*	<.001^*	.005^*	<.001^*
IL‐6	(33.35–141.60)^f	(12.40–29.32)	(17.20–39.56)	<.001^*	<.001^*	.005^*	<.001^*
IL‐8	66.28	70.50	69.27	<.001^*	<.001^*	.010^*	<.001^*
IL‐8	(66.02–66.85)	(68.03–76.85)	(66.49–74.21)	<.001^*	<.001^*	.010^*	<.001^*
IL‐10	20.29	5.19	5.56	<.001^*	<.001^*	.096	<.001^*
IL‐10	(11.09–42.03)	(3.29–6.54)	(4.29–7.19)	<.001^*	<.001^*	.096	<.001^*
IP‐10	1124.53	58.05	61.53	<.001^*	<.001^*	.327	<.001^*
IP‐10	(444.24–2173.64)	(41.99–75.50)	(45.91–79.04)	<.001^*	<.001^*	.327	<.001^*
MCP‐1	195.40	86.83	54.22	<.001^*	<.001^*	.004^*	<.001^*
MCP‐1	(80.68–405.09)	(52.18–126.95)	(35.44–103.75)	<.001^*	<.001^*	.004^*	<.001^*
MIP‐1α	684.80	684.16	683.28	.157	.001^*	.010^*	.0011^*
MIP‐1α	(682.80–711.08)	(682.85–689.99)	(681.93–686.22)	.157	.001^*	.010^*	.0011^*
IFN‐γ^g	36.86 (18.38–83.93)	10.36 (3.81–42.01)	6.06 (3.91–12.72)	.003^*	<.001^*	.665	<.001^*
	(n = 73)	(n = 25)	(n = 23)	.003^*	<.001^*	.665	<.001^*
TGF‐β1	980.25	3654.05	4694.88	<.001^*	<.001^*	<.001^*	<.001^*
	(430.62–1609.65)	(2915.33–4268.67)	(3597.08–5083.66)

TNF‐α^g	73.78 (27.27–203.28)	85.72 (40.34–104.05)	56.95 (36.54–187.91)	.726	.901	.767	.954
TNF‐α^g	(n = 20)	(n = 13)	(n = 11)	.726	.901	.767	.954
RANTES	1236.15	1671.83	2011.91	<.001^*	<.001^*	.033	<.001^*
RANTES	(787.60–1636.08)	(1330.82–2089.53)	(1300.61–2630.62)	<.001^*	<.001^*	.033	<.001^*

Abbreviations: IFN‐γ, interferon‐γ; IL‐6, interleukin‐6; IP‐10, IFN‐inducible protein‐10; MCP‐1, monocyte chemoattractant protein‐1; MIP‐1α, macrophage inflammatory protein‐1α; RANTES, regulated upon activation normal T cell expressed and secreted factor; TNF‐α, tumor necrosis factor‐α; TGF‐β1, transforming growth factor‐β1.

Note: Unit: pg/ml.

^{^a}

The cytokine levels were measured in SFTS patients on admission.

^{^b}

The SFTS patient group compared with the healthy people group.

^{^c}

The SFTS patient group compared with the asymptomatic infected person group.

^{^d}

The healthy people group compared with the asymptomatic infected person group.

^{^e}

Comparison among the three groups.

^{^f}

Denotes the median (IQ).

^{^g}

Denotes there was a lack of data.

Denotes had statistical differences.