. 2021 Mar 26;99(7):1864–1884. doi: 10.1002/jnr.24834

TABLE 3.

Region‐ or treatment‐dependent expression in CD68⁺, CD206⁺, CD68⁺CD206⁺, and CD68⁻CD206⁺ cells

Phenotype	ROI	Number of cells (cells/mm²)			p values
Phenotype	ROI	TBI	Sham	ES	TBI vs. sham	TBI vs. ES	Sham vs. ES
CD68⁺ (Figure 3c)	ROI₁	646.5 ± 344.5	825.1 ± 548.3	837.8 ± 381.1	p = 0.7278	p = 0.4426	p > 0.9999
CD68⁺ (Figure 3c)	ROI₂	761.9 ± 351.2	775.2 ± 358.3	644.1 ± 271.6	p > 0.9999	p = 0.8582	p = 0.8833
p values (ROI₁ vs. ROI₂)		p = 0.9144	p = 0.9993	p = 0.2700
CD206⁺ (Figure 3d)	ROI₁	427.9 ± 211.5	505.8 ± 534.6	791.5 ± 424.4	p = 0.9876	p = 0.0044	p = 0.1114
CD206⁺ (Figure 3d)	ROI₂	174.1 ± 277.0	73.4 ± 42.6	575.0 ± 338.6	p = 0.9620	p = 0.0007	p = 0.0003
p values (ROI₁ vs. ROI₂)		p = 0.1783	p = 0.0194	p = 0.1241
CD68⁺CD206⁺ (Figure 3e)	ROI₁	254.3 ± 154.2	404.8 ± 532.6	511.1 ± 334.4	p = 0.6752	p = 0.0276	p = 0.8645
CD68⁺CD206⁺ (Figure 3e)	ROI₂	117.8 ± 230.3	37.4 ± 26.3	400.9 ± 263.9	p = 0.9697	p = 0.0079	p = 0.0031
p values (ROI₁ vs. ROI₂)		p = 0.6667	p = 0.0177	p = 0.6466
CD68⁻CD206⁺ (Figure 3f)	ROI₁	174.6 ± 127.1	101.1 ± 77.4	280.4 ± 189.6	p = 0.5537	p = 0.0423	p = 0.0003
CD68⁻CD206⁺ (Figure 3f)	ROI₂	56.3 ± 59.7	36.0 ± 27.9	174.2 ± 117.4	p = 0.9974	p = 0.0117	p = 0.0137
p values (ROI₁ vs. ROI₂)		p = 0.0342	p = 0.7636	p = 0.0108
Two‐way ANOVA tests with Tukey's post hoc analysis

Data are reported as mean ± SD. N = 4, 3, 6 animals with two tissue slices analyzed for untreated TBI, sham, ES.