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Overview of the study design: all participants were screened (1 visit) to test eligibility and had a run‐in phase (2 visits) to make participants familiarized with all measurements. During the study period of 90 days, participants had around 2–3 visits per week, with ~20 visits in the pre‐challenge phase (60 days) and ~10 visits in the post‐challenge phase (30 days)
