TABLE 3.

Correlation between total change in eNose fluctuations and symptoms or inflammation

	Healthy				Asthma
	Pre		Post		Pre		Post
	ρ (95% CI)	p‐value	ρ (95% CI)	p‐value	ρ (95% CI)	p‐value	ρ (95% CI)	p‐value
FeNO	−.16 (−0.64–0.47)	.62	.20 (−0.52–0.73)	.53	.00 (−0.73–0.61)	1.00	.03 (−0.72–0.61)	.94
WURSS−21	‐	‐	.41 (−0.23–0.79)	.18	‐	‐	−.14 (−0.72–0.55)	.67
IFN‐γ	−.15 (−0.71–0.52)	.65	.19 (−0.45–0.76)	.56	.12 (−0.59–0.68)	.70	−.03 (−0.66–0.56)	.92
IL−1β	.17 (−0.54–0.75)	.60	.41 (−0.27–0.87)	.18	−.36 (−0.87–0.37)	.26	−.49 (−0.89–0.21)	.11
IL−10	−.13 (−0.77–0.63)	.70	.30 (−0.41–0.83)	.34	−.28 (−0.73–0.30)	.38	−.22 (−0.77–0.42)	.48
IL−13	.26 (−0.40–0.73)	.42	.34 (−0.41–0.87)	.28	−.20 (−0.77–0.48)	.54	−.49 (−0.82–0.12)	.11
IL−17A	.06 (−0.55–0.62)	.85	.14 (−0.53–0.72)	.67	−.37 (−0.89–0.33)	.24	−.45 (−0.87–0.18)	.14
IL−33	−.11 (−0.69–0.57)	.73	−.05 (−0.61–0.51)	.89	.00 (−0.70–0.66)	1.00	.01 (−0.67–0.80)	.99
IL−6	.33 (−0.32–0.82)	.30	.05 (−0.57–0.68)	.89	−.26 (−0.81–0.44)	.42	−.41 (−0.76–0.24)	.18
IL−8	.29 (−0.40–0.80)	.37	.29 (−0.33–0.81)	.37	−.50 (−0.98–0.10)	.10	−.60 (−0.89–−0.03)	.04
IP−10	−.38 (−0.93–0.41)	.22	−.01 (−0.60–0.58)	.97	−.19 (−0.80–0.43)	.56	−.36 (−0.89–0.38)	.26
TNF‐α	.22 (−0.45–0.73)	.50	.25 (−0.41–0.83)	.43	−.45 (−0.90–0.23)	.14	−.55 (−0.92–0.01)	.07

For FeNO, WURSS‐21, and the cytokine levels, individual means were calculated based on 10 days pre‐ or post‐challenge; WURSS‐21 scores were only available post‐challenge. Next, Spearman's rank correlation coefficients (ρ) and bootstrapped (n = 1000) 95% confidence intervals (CI) were calculated between the total change in eNose fluctuations and FeNO, WURSS‐21, or cytokines in nasal lavage. Results with p‐values <.05 and/or ρ ≥ .50 are marked in bold.

Abbreviations: FeNO, fractional exhaled nitric oxide; WURSS, Wisconsin Upper Respiratory Symptom Survey.