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. Author manuscript; available in PMC: 2021 Aug 12.
Published in final edited form as: Bone Marrow Transplant. 2017 Dec 21;53(3):315–325. doi: 10.1038/s41409-017-0034-z

Table 3.

Univariate analysis for overall survival at 18 months.

n Hazard Ratio 95% confidence
interval
P-value
First line steroids to Pentostatin, days
<=10 days 20 Reference
>10 days 40 1.1 0.6-2.0 0.8
Pentostatin used as
second line therapy 22 Reference
third line therapy 38 0.9 0.5-1.7 0.8
Age at Pentostatin
<=60 years 46 Reference
>60 years 14 1.9 1.01-3.7 0.045
Female-to-male gender Mismatch
No 35 Reference
Yes 25 0.7 0.2-1.9 0.4
Donor type
HLA-matched related 19 0.7 0.2-2.2 0.5
HLA-matched unrelated 35
Haploidentical 3
Cord blood 3
Graft source
Bone marrow 10 Reference
Peripheral blood 46 1.3 0.6-2.9 0.5
Cord blood 4 Excluded
Conditioning
Myeloablative 38 Reference
Non-myeloablative 22 1.4 0.8-2.6 0.2
Overall grade (at diagnosis)
Grade 2 11 Reference
Grade 3-4 49 1.9 0.9-4.3 0.1
GVHD organs
Skin (Reference no skin) 12 2 1.02-4.1 0.04
UGI (Reference no UGI) 27 0.95 0.5-1.7 0.9
LGI (Reference no LGI) 47 0.4 0.2-0.8 0.01
Liver (Reference no liver) 26 1.9 1.05-3.3 0.03
GVHD organ combination
LGI only 28 Reference
Liver only 10 3.3 1.4-7.3 0.004
LGI + Liver 10 1.4 0.6-3.3 0.4
LGI + Liver + Skin 6 3.1 1.02-9.6 0.05
Skin + LGI 4 2.5 0.96-6.3 0.06
Skin only 1 Excluded
Skin + Liver 1 Excluded