Table 3.

Median[IQR] values for hemodynamics calculated in the training and testing dataset based on invasive (IVUS/OCT) and noninvasive (CTA) imaging.

	Training Data			Testing Data
	CTA Median [IQR]	OCT/IVUS Median [IQR]	p-value	CTA Median [IQR]	OCT/IVUS Median [IQR]	p-value
${\overline{TAESS}}_{seg}$ (dyne/cm2)	50.1[25.8–90.1]	31.7 [19.3–62.4]	<0.001	30.1[17.1–83.8]	15.8[8.8–63.4]	<0.001
${\overline{TAESS}}_{arc}$ (dyne/cm2)	47.7[24.1–90.0]	29.9 [18.1–62.4]	<0.001	29.4[16.2–74.7]	15.0[8.9–57.4]	<0.001
$TAES{S}_{min}$ (dyne/cm2)	16.2[6.7–34.7]	10.3[4.4–19.5]	0.006	13.4[6.1–25.9]	6.0[4.1–17.1]	<0.001
$TAES{S}_{max}$ (dyne/cm2)	90.3[42.8–167.6]	55.3[34.0–117.3]	0.007	51.8[27.4–128.4]	25.6[18.0–120.9]	<0.001
${\overline{OSI}}_{seg}$ (x10−4)	6.3[2.0–34.0]	1.1[2.0–51.0]	0.15	8.5[3.0–24.0]	23.0[7.0–57.0]	<0.001
${\overline{P}}_{seg}$ (mmHg)	84.8[52.5–100.5]	69.2[43.1–87.6]	<0.001	96.3[70.9–98.9]	78.8[78.5–90.3]	<0.001
Dia (mm)	2.2[1.8–2.7]	2.4[2.0–3.1]	<0.001	2.5[1.9–3.0]	3.1[2.2–3.6]	<0.001

${\overline{TAESS}}_{seg}$: segment-averaged time averaged endothelial shear stress; ${\overline{TAESS}}_{arc}$: arc-averaged time averaged endothelial shear stress; $TAES{S}_{min},TAES{S}_{min}$: minimum and maximum time averaged endothelial shear stress in each 2mm segment; ${\overline{OSI}}_{seg}$: segment-averaged oscillatory shear index; ${\overline{P}}_{seg}$: segment-averaged time averaged pressure; Dia: lumen diameter