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. 2021 Jul 27;8(8):ofab352. doi: 10.1093/ofid/ofab352

Table 4.

Associations, Measured by Odds Ratios, and 95% CIs, Between Individual Persistent Symptoms and Physical and Emotional Health Indicators; Limited to Symptoms That Were Reported by at Least 5 Participants

Persistent Symptoms Physical Health Worse Than Before Acute COVID-19 Physical Health Affects Daily Activities Emotional Health Affects Daily Activities
OR (95% CI) OR (95% CI) OR (95% CI)
 Fatigue 10.48 (5.47–20.07) 10.35 (5.36–19.98) 2.56 (1.41–4.64)
 Dyspnea on exertion 8.34 (4.06–17.15) 13.68 (5.98–31.28) 2.16 (1.09–4.25)
 Mental fog 9.83 (4.63–20.85) 12.41 (5.41–28.48) 3.06 (1.53–6.10)
 Difficulty sleeping 7.42 (3.36–16.35) 7.17 (3.16–16.27) 3.21 (1.52–6.79)
 Loss of smell 4.32 (2.05–9.12) 4.69 (2.19–10.05) 1.46 (0.68–3.12)
 Headache 3.99 (1.84–8.66) 12.24 (4.81–31.17) 3.46 (1.62–7.40)
 Dry cough 2.34 (1.02–5.36) 2.01 (0.89–4.54) 1.09 (0.45–2.62)
 Feeling depressed 10.35 (4.14–25.9) 7.26 (2.93–18.02) 5.53 (2.35–12.99)
 Muscle aches 10.47 (3.95–27.81) 6.32 (2.52–15.87) 2.68 (1.15–6.23)
 Joint pains 17.1 (5.56–52.59) 12.06 (3.95–36.85) 1.77 (0.73–4.31)
 Weakness 10.76 (3.75–30.84) 11.24 (3.66–34.51) 1.55 (0.62–3.89)
 Heart palpitations 4.46 (1.79–11.08) 16.17 (4.62–56.53) 2.38 (0.97–5.84)
 Anxiety/ nervousness 3.60 (1.40–9.25) 7.07 (2.46–20.32) 4.71 (1.78. 12.43)
 Chest tightness/pain 7.48 (2.73–20.51) 5.38 (1.97–14.65) 1.85 (0.72–4.79)
 Loss/change in taste 4.67 (1.71–12.78) 2.95 (1.12–7.76) 1.60 (0.60–4.28)
 Sinus congestion 2.79 (1.03–7.53) 5.91 (2.01–17.32) 1.77 (0.65–4.82)
 Irritability 3.15 (1.14–8.74) 7.42 (2.32–23.72) 6.02 (2.02–17.9)
 Back pain 4.85 (1.66–14.15) 9.95 (2.73–36.22) 5.40 (1.78–16.32)
 Dizziness 6.43 (1.88–22.05) 7.19 (1.90–27.22) 3.63 (1.12–11.78)
 Rhinorrhea 3.73 (1.10–12.60) 6.31 (1.63–24.37) 2.09 (0.62–7.06)
 Ear fullness 4.68 (1.28–17.08) 9.51 (1.98–45.76) 3.86 (1.06–14.04)
 Heartburn 3.06 (0.86–10.89) 5.45 (1.38–21.61) 2.53 (0.71–8.97)
 Shortness of breath at rest 11.19 (2.27–55.18) 4.62 (1.13–18.91) 1.23 (0.30–5.02)

Abbreviations: COVID-19, coronavirus disease 2019; OR, odds ratio.