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. Author manuscript; available in PMC: 2022 Jul 8.
Published in final edited form as: J Med Chem. 2021 Jun 18;64(13):9271–9278. doi: 10.1021/acs.jmedchem.1c00512

Figure 1.

Figure 1.

Stability of RgIA4 and RgIA-5474 in 25% human serum. Top panel: HPLC traces of a mixture (~1:1) of the globular and ribbon forms of the reference peptides RgIA4 and RgIA-5474. Bottom panel: serum stability at 24h (n=6). The reaction was monitored by RP-HPLC, using a C18 column and the gradient: ranging from 10% to 50% of buffer B in 40 min, with a flow rate of 1mL/min. Serum stability data for RgIA5 is shown in Figure S10.