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Characteristics of microglial clustering in the PMC. a The density of microglial clusters was significantly greater in the PMC of HPCs and AD cases compared to controls. b Microglial clusters were more frequently associated with fibrillar neuritic plaques in a combined group analysis; Spearman ρ = 0.54, p = 0.006. †Significantly reduced compared to PMC of HPCs; ‡Significantly reduced compared to PMC of AD cases. *†‡p<0.05.
