Table 3.

Risk factors associated with severe COVID-19 patients.

Risk factors	Univariable OR (95% CI)	P value	Multivariable OR (95% CI)	P value
Age, years	1.064 (1.034–1.094)	.000	1.069 (1.036–1.103)	<.001
Hypertension	6.190 (2.307–16.614)	.000	7.310 (1.705–31.350)	.007
Diabetes	4.075 (0.827–20.088)	.084
SOFA score	5.328 (2.932–9.681)	.000	5.851 (3.044–11.245)	<.001
IL-6	1.021 (1.002–1.041)	.029
White blood cells	1.196 (1.078–1.327)	.001	1.195 (1.060–1.346)	.004
Neutrophils	1.232 (1.107–1.371)	.000	1.210 (1.084–1.351)	.001
Lymphocytes	0.222 (0.094–0.526)	.001	0.280 (0.107–0.730)	.009
Red blood cell	0.520 (0.278–0.973)	.041
hs-CRP	1.026 (1.008–1.045)	.006
Direct bilirubin	1.207 (1.016–1.434)	.032
Alkaline phosphatase	1.020 (1.002–1.039)	.032	1.032 (1.007–1.057)	.013
Gamma-glutamyl transpeptidase	1.006 (1.001–1.012)	.027
Urea nitrogen	1.484 (1.173–1.876)	.001	1.480 (1.154–1.898)	.002
Uric acid	0.993 (0.989–0.998)	.005
Cystatin C	33.239 (4.316–255.970)	.001	30.893 (2.988–319.403)	.004
Sodium	0.819 (0.715–0.937)	.004
Chlorine	0.844 (0.743–0.960)	.010
Phosphorus	0.068 (0.012–0.380)	.002	0.055 (0.007–0.462)	.008
CK-MB	1.092 (1.027–1.161)	.005	1.086 (1.017–1.161)	.030
Procalcitonin	5.689 (0.710–45.575)	.102
Hemoglobin	0.980 (0.960–1.000)	.056
Platelets	1.004 (0.999–1.009)	.096
Total bilirubin	1.057 (0.995–1.123)	.072
Indirect bilirubin	1.068 (0.981–1.163)	.128
Potassium	0.608 (0.325–1.139)	.120
Calcium	0.220 (0.032–1.485)	.120
Myoglobin	1.004 (0.999–1.009)	.112