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. 2021 Aug 2;17(8):e1008904. doi: 10.1371/journal.pcbi.1008904

Table 2. Genotype determination performance.

Genotype determination performance table comparing the genotypes determined by PING to the validation genotypes for each dataset. Possible outcomes are ‘Match’, where the determined component allele matches the validation allele, ‘Mismatch’, where the determined component allele does not match the validation allele, or ‘Unresolved’, where PING was unable to determine a genotype, but the validation allele was not marked as unresolved. The coloring signifies concordance level, where green is 0–10% discordant, yellow is 10–15% discordant, and red is over 15% discordant.

Gene Dataset Match Mismatch Unresolved N
KIR3DL3 European 0.959 0.009 0.032 686
Synthetic 0.960 0.000 0.040 100
Khoesan 0.887 0.062 0.050 80
KIR2DS2 European 0.975 0.012 0.013 686
Synthetic 0.940 0.040 0.020 100
Khoesan 0.835 0.005 0.160 188
KIR2DL23 European 0.965 0.003 0.032 656
Synthetic 0.850 0.020 0.130 100
Khoesan 0.810 0.042 0.149 168
KIR2DL5A/B European 0.927 0.044 0.029 687
Synthetic 0.856 0.106 0.038 104
Khoesan 0.857 0.071 0.071 126
KIR2DS35 European 0.982 0.006 0.012 683
Synthetic 0.923 0.019 0.058 104
Khoesan 0.871 0.052 0.078 116
KIR2DP1 European 0.890 0.007 0.103 672
Synthetic 0.971 0.000 0.029 103
Khoesan 0.721 0.012 0.267 86
KIR2DL1 European 0.961 0.009 0.030 666
Synthetic 0.883 0.019 0.097 103
Khoesan 0.803 0.045 0.152 132
KIR3DP1 European - - - -
Synthetic 0.773 0.055 0.173 110
Khoesan - - - -
KIR2DL4 European 0.980 0.007 0.013 685
Synthetic 1.000 0.000 0.000 110
Khoesan 0.961 0.006 0.032 154
KIR3DL1S1 European 0.962 0.006 0.032 686
Synthetic 0.955 0.000 0.045 110
Khoesan 0.873 0.028 0.099 142
KIR2DS1 European 0.985 0.003 0.012 682
Synthetic 0.900 0.000 0.100 100
Khoesan 0.995 0.000 0.005 198
KIR2DS4 European 0.943 0.044 0.013 685
Synthetic 0.940 0.020 0.040 100
Khoesan 0.793 0.051 0.157 198
KIR3DL2 European 0.965 0.008 0.028 648
Synthetic 0.990 0.010 0.000 100
Khoesan 0.819 0.011 0.170 188