Table 1. Model probabilities.
Parameter | Event | Total sample | Probability | Distribution | Source |
---|---|---|---|---|---|
No-mouthwash-arm | |||||
Patients with pneumonia | |||||
Pneumonia | 39 | 931 | 0.04 | Βeta | ASOS [1] |
Critical care unit | 21 | 39 | 0.54 | Βeta | ASOS [1] |
MV | - | - | 0.25 | Βeta | Expert Opinion |
Died after MV | 10 | 21 | 0.48 | Βeta | ASOS [1] |
Died (Critical care unit, No-MV) | 17 | 42 | 0.40 | Βeta | ASOS [1] |
Died in general ward | 3 | 75 | 0.04 | Βeta | RECON [17] |
Patients with no pneumonia | |||||
Critical care unit | 85 | 887 | 0.10 | Βeta | ASOS [1] |
MV | - | - | 0.24 | Fixed | Expert Opinion |
Died after MV | - | - | 0.04 | Fixed | Expert Opinion |
Died after no MV in critical care unit | 29 | 85 | 0.34 | Βeta | ASOS [1] |
Died in general ward | 25 | 802 | 0.03 | Βeta | ASOS [1] |
Mouthwash arm | |||||
Patients with pneumonia | |||||
Pneumonia | 27 | 931 | 0.03 | Βeta | ASOS [1] but reduced value in no-mouthwash arm by 0.3 RRR |
Critical care unit | 15 | 39 | 0.38 | Βeta | ASOS [1], Reduced value in no-mouthwash arm by 0.3 RRR |
MV | - | - | 0.18 | Fixed | Expert opinion, Reduced value in no-mouthwash arm by 0.3 RRR |
Died after MV | 7 | 21 | 0.33 | Βeta | ASOS [1], Reduced value in no-mouthwash arm by 0.3 RRR |
Died after no MV in critical care unit | 12 | 42 | 0.28 | Βeta | ASOS [1], Reduced value in no-mouthwash arm by 0.3 RRR |
Died in general ward | 3 | 75 | 0.04 | Βeta | RECON [17], Assumed to be the same as in control arm |
Patients with no pneumonia | |||||
Critical care unit | 85 | 887 | 0.10 | Βeta | ASOS [1], Reduced value in no-mouthwash arm by 0.3 RRR |
MV | - | - | 0.24 | Fixed | Expert opinion, assumed to be the same as in no-mouthwash-arm |
Dead after MV | - | - | 0.04 | Fixed | Expert opinion, Assumed to be the same as in control arm |
Dead (Critical care unit, No-MV) | 29 | 85 | 0.34 | Beta | ASOS [1], Assumed to be the same as in control arm |
Dead in general ward | 25 | 802 | 0.03 | Βeta | ASOS [1] Assumed to be the same as in control arm |
*MV = Mechanical ventilation.