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. 2021 Aug 12;16(8):e0254698. doi: 10.1371/journal.pone.0254698

Table 4. Parameter values used in deterministic sensitivity analysis.

Variable Base case value Lower bound Upper bound Source
Costs
Pneumonia cost $3,752 $121 $5,804 Lower bound Eber et al, Upper bound Thompson et al [25, 26]
Bed day $71 $57 $85 -20%, +20%
Relative Risk Reduction
RRR 0.30 0.2, 0.10 0.05, 0.01 -10 percentage points, -10 percentage points, -5 percentage points, -4 percentage points
No mouthwash
Pneumonia patients
Pneumonia 0.04 0.03 0.05 -20%, +20%
Critical care unit 0.54 0.43 0.64 -20%, +20%
MV 0.25 0.10 0.40 -60%+60%
No pneumonia patients
Critical care unit 0.10 0.08 0.11 -20%, +20%
MV 0.24 0.14 0.30 -40%+20%
Dead (critical care unit No-MV) 0.04 0.01 0.08 -80%, +90%
No mouthwash, Mean LoS (days)
Pneumonia, critical care unit 18.99 15.19 22.79 -20%, +20%
Pneumonia, critical care unit, MV 21.12 16.90 25.34 -20%, +20%
Pneumonia, general ward 11.36 9.09 13.63 -20%, +20%
Mouthwash
Pneumonia patients
Pneumonia 0.04 0.03 0.05 -20%, +20%
Critical care unit 0.53 0.43 0.64 -20%+20%
MV 0.25 0.10 0.40 -60%, +60%
No mouthwash patients
Critical care unit 0.10 0.08 0.11 -20%, +20%
MV 0.24 0.14 0.30 -40%+20%
Dead (critical care unit No-MV) 0.04 0.01 0.08 -80%, +90%
Mouthwash, Mean LoS (days)
Pneumonia, critical care unit 18.99 15.19 22.79 -20%, +20%
Pneumonia, critical care unit, MV 21.12 16.90 25.34 -20%, +20%
Pneumonia, general ward 11.36 9.09 13.63 -20%, +20%
Extreme cases
No patient on MV - - - Assumption
Best case scenario - - - Assumption
Worst case scenario - - - Assumption

*MV = mechanical ventilation.