Table 4. Parameter values used in deterministic sensitivity analysis.
Variable | Base case value | Lower bound | Upper bound | Source |
---|---|---|---|---|
Costs | ||||
Pneumonia cost | $3,752 | $121 | $5,804 | Lower bound Eber et al, Upper bound Thompson et al [25, 26] |
Bed day | $71 | $57 | $85 | -20%, +20% |
Relative Risk Reduction | ||||
RRR | 0.30 | 0.2, 0.10 | 0.05, 0.01 | -10 percentage points, -10 percentage points, -5 percentage points, -4 percentage points |
No mouthwash | ||||
Pneumonia patients | ||||
Pneumonia | 0.04 | 0.03 | 0.05 | -20%, +20% |
Critical care unit | 0.54 | 0.43 | 0.64 | -20%, +20% |
MV | 0.25 | 0.10 | 0.40 | -60%+60% |
No pneumonia patients | ||||
Critical care unit | 0.10 | 0.08 | 0.11 | -20%, +20% |
MV | 0.24 | 0.14 | 0.30 | -40%+20% |
Dead (critical care unit No-MV) | 0.04 | 0.01 | 0.08 | -80%, +90% |
No mouthwash, Mean LoS (days) | ||||
Pneumonia, critical care unit | 18.99 | 15.19 | 22.79 | -20%, +20% |
Pneumonia, critical care unit, MV | 21.12 | 16.90 | 25.34 | -20%, +20% |
Pneumonia, general ward | 11.36 | 9.09 | 13.63 | -20%, +20% |
Mouthwash | ||||
Pneumonia patients | ||||
Pneumonia | 0.04 | 0.03 | 0.05 | -20%, +20% |
Critical care unit | 0.53 | 0.43 | 0.64 | -20%+20% |
MV | 0.25 | 0.10 | 0.40 | -60%, +60% |
No mouthwash patients | ||||
Critical care unit | 0.10 | 0.08 | 0.11 | -20%, +20% |
MV | 0.24 | 0.14 | 0.30 | -40%+20% |
Dead (critical care unit No-MV) | 0.04 | 0.01 | 0.08 | -80%, +90% |
Mouthwash, Mean LoS (days) | ||||
Pneumonia, critical care unit | 18.99 | 15.19 | 22.79 | -20%, +20% |
Pneumonia, critical care unit, MV | 21.12 | 16.90 | 25.34 | -20%, +20% |
Pneumonia, general ward | 11.36 | 9.09 | 13.63 | -20%, +20% |
Extreme cases | ||||
No patient on MV | - | - | - | Assumption |
Best case scenario | - | - | - | Assumption |
Worst case scenario | - | - | - | Assumption |
*MV = mechanical ventilation.