Table 6. Scenario 1 deterministic sensitivity analysis results.
| Parameter | Parameter value | Difference in costs ($) | Difference in costs (R) | Incremental benefits | Dominance break off point | ICER |
|---|---|---|---|---|---|---|
| Base case | N/A | -283 | -4,913 | 0.0126 | $289 | Mouthwash dominates |
| Relative Risk Reduction | ||||||
| RRR | 0.20 | -197 | -3,423 | 0.0084 | $203 | Mouthwash dominates |
| 0.10 | -101 | -1,754 | 0.0042 | $107 | Mouthwash dominates | |
| 0.05 | -49 | -851 | 0.0021 | $55 | Mouthwash dominates | |
| 0.01 | -6 | -95 | 0.0004 | $11 | Mouthwash dominates | |
| Costs | ||||||
| Pneumonia | $121 | -4 | -69 | 0.0004 | Mouthwash dominates | |
| $5,804 | -6 | -110 | 0.0004 | Mouthwash dominates | ||
| Bed day | $57 | -6 | -96 | 0.0004 | Mouthwash dominates | |
| $85 | -5 | -95 | 0.0004 | Mouthwash dominates | ||
| Probabilities | ||||||
| No-Mouthwash | ||||||
| Pneumonia | 0.03 | 167 | 2,895 | -0.0115 | N/A | No-mouthwash dominate |
| 0.05 | -123 | -2,135 | 0.0085 | N/A | Mouthwash dominates | |
| Pneumonia, critical care unit | 0.43 | 95 | 1,642 | 0.0004 | N/A | $225,863 |
| 0.64 | -99 | -1,722 | 0.0004 | N/A | Mouthwash dominates | |
| Pneumonia, MV | 0.10 | 4 | 65 | 0.0004 | N/A | $8,962 |
| 0.40 | -15 | -252 | 0.0004 | N/A | Mouthwash dominates | |
| No Pneumonia, critical care unit | 0.08 | 273 | 4,743 | 0.0004 | N/A | $652,472 |
| 0.11 | -284 | -4,934 | 0.0004 | N/A | Mouthwash dominates | |
| No Pneumonia, MV | 0.14 | 14 | 245 | 0.0004 | N/A | $33,686 |
| 0.30 | -18 | -314 | 0.0004 | N/A | Mouthwash dominates | |
| No Pneumonia, no MV, dead | 0.01 | -6 | -95 | 0.0004 | N/A | Mouthwash dominates |
| 0.08 | -6 | -95 | 0.0004 | N/A | Mouthwash dominates | |
| Mouthwash | ||||||
| Pneumonia | 0.03 | -170 | -2,956 | 0.0119 | N/A | Mouthwash dominates |
| 0.05 | 117 | 2,031 | -0.0081 | N/A | No-mouthwash dominates | |
| Pneumonia, critical care unit | 0.43 | -103 | -1,786 | 0.0004 | N/A | Mouthwash dominates |
| 0.64 | 92 | 1,595 | 0.0004 | N/A | $219,374 | |
| Pneumonia, MV | 0.10 | -14 | -251 | 0.0004 | N/A | Mouthwash dominates |
| 0.40 | 3 | 60 | 0.0004 | N/A | $8,312 | |
| No Pneumonia, critical care unit | 0.08 | -284 | -4,936 | 0.0004 | N/A | Mouthwash dominates |
| 0.11 | 273 | 4,745 | 0.0004 | N/A | $652,763 | |
| No Pneumonia, MV | 0.14 | -25 | -436 | 0.0004 | N/A | Mouthwash dominates |
| 0.3 | 7 | 123 | 0.0004 | N/A | $16,890 | |
| No Pneumonia, No MV, dead | 0.01 | -6 | -95 | 0.0004 | N/A | Mouthwash dominates |
| 0.08 | -6 | -95 | 0.0004 | N/A | Mouthwash dominates | |
| Length of stay (mean days) | ||||||
| No-Mouthwash | ||||||
| General ward | 9.09 | -2 | -42 | 0.0004 | 7.34 | Mouthwash dominates |
| 13.63 | -9 | -149 | 0.0004 | Mouthwash dominates | ||
| Critical care unit | 15.19 | 21 | 359 | 0.0004 | 18.19 | $49,378 |
| 22.79 | -32 | -550 | 0.0004 | Mouthwash dominates | ||
| MV | 16.9 | -3 | -58 | 0.0004 | 10.30 | Mouthwash dominates |
| 25.34 | -8 | -133 | 0.0004 | Mouthwash dominates | ||
| Mouthwash | ||||||
| General ward | 9.09 | -9 | -149 | 0.0004 | 15.38 | Mouthwash dominates |
| 13.63 | -2 | -42 | 0.0004 | Mouthwash dominate | ||
| Critical care unit | 15.19 | -31 | -536 | 0.0004 | 19.81 | Mouthwash dominates |
| 22.79 | 20 | 345 | 0.0004 | $47,521 | ||
| MV | 16.9 | -8 | -132 | 0.0004 | 32.27 | Mouthwash dominates |
| 25.34 | -3 | -59 | 0.0004 | Mouthwash dominates | ||
| Extreme case analysis | ||||||
| No patient on MV | N/A | -5 | -88 | 0.0004 | N/A | Mouthwash dominates |
| Best case scenario | N/A | -277 | -4,801 | 0.0119 | N/A | Mouthwash dominates |
| Worst case scenario | N/A | 280 | 4,866 | -0.0081 | N/A | No-mouthwash dominates |
*MV = mechanical ventilation.