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. 2021 Aug 12;16(8):e0256063. doi: 10.1371/journal.pone.0256063

Table 5. Cardiovascular outcomes as a function of time period.

Time period Outcomes
Variable Baseline (M±SD) Physical distancing (M±SD) Difference (PD-BL; M±SEM) Effect size (95% CL)
Resting heart rate (bpm)
2019 55.15 ± 0.8 54.64 ± 0.76 -0.51 ± 0.011** -0.65 (-0.69, -0.62)
2020 55.09 ± 0.81 54.2 ± 0.55 -0.90 ± 0.009** -1.29 (-1.32, -1.25)
    18–25 year-olds 53.82 ± 1.06 52.98 ± 0.58 -0.84 ± 0.048** -0.98 (-1.14, -0.82)
    25–40 year-olds 54.26 ± 0.97 53.31 ± 0.61 -0.95 ± 0.016** -1.17 (-1.23, -1.12)
    40–55 year-olds 56.11 ± 0.68 55.24 ± 0.53 -0.87 ± 0.014** -1.43 (-1.49, -1.36)
    55–80 year-olds 56.21 ± 0.52 55.35 ± 0.47 -0.86 ± 0.020** -1.74 (-1.85, -1.62)
    Females 56.74 ± 0.77 55.89 ± 0.52 -0.84 ± 0.017** -1.29 (-1.37, -1.22)
    Males 54.43 ± 0.85 53.5 ± 0.58 -0.93 ± 0.012** -1.28 (-1.32, -1.23)
Heart rate variability (ms)
2019 61.31 ± 2.04 64.28 ± 4.2 2.97 ± 0.045** 0.90 (0.86, 0.94)
2020 65.85 ± 2.28 66.82 ± 1.4 0.98 ± 0.026** 0.51 (0.47, 0.55)
    18–25 year-olds 93.77 ± 4.25 93.87 ± 2.35 0.09 ± 0.193 0.03 (-0.13, 0.19)
    25–40 year-olds 74.26 ± 2.77 75.58 ± 1.69 1.32 ± 0.045** 0.58 (0.52, 0.63)
    40–55 year-olds 54.15 ± 1.52 55.11 ± 1.12 0.96 ± 0.031** 0.72 (0.65, 0.78)
    55–80 year-olds 50.99 ± 1.56 51.98 ± 1.15 0.99 ± 0.054** 0.72 (0.61, 0.83)
    Females 67.35 ± 2.2 68.4 ± 1.48 1.05 ± 0.048** 0.56 (0.49, 0.63)
    Males 65.24 ± 2.34 66.18 ± 1.44 0.94 ± 0.031** 0.48 (0.44, 0.53)

Notes: BL = baseline; PD = physical distancing; bpm = beats per minute; ms = milliseconds

* = p-value <0.05

** = p-value <0.001.