Figure 3.

The comparison of T cell subsets distribution in healthy controls and patients with NMOSD. (A) Proportions of T follicular helper (Tfh: CD4⁺CXCR5⁺PD-1^high) and subsets among total CD4⁺ cells in patients with NMOSD and healthy controls (HC); (B) Proportions of peripheral T helper (Tph: CD4⁺CXCR5^-PD-1^high) and subsets. Tfh1 (CXCR3⁺CCR6^–), Tfh2 (CXCR3^–CCR6^–), and Tfh17 (CXCR3^–CCR6⁺), Tph1 (CXCR3⁺CCR6^–), Tph2 (CXCR3^–CCR6^–), and Tph17 (CXCR3^–CCR6⁺). Unpaired, two-tailed Student’s t tests were used. HC: n=20; NMOSD: n=26.