TABLE 1.
Association between COL1A1 rs1107946 polymorphism and fatigue fracture in J-HAP (n = 1636).
| Genotype | n (%) | Dominant | Recessive | Additive | |||||
|---|---|---|---|---|---|---|---|---|---|
| Fatigue Fracture | No-Fatigue Fracture | OR (95% CI) AIC | P* | OR (95% CI) AIC | P* | OR (95% CI) AIC | P* | ||
| rs1107946 | CC+ AC vs AA | CC vs AC + AA | CC vs AC vs AA | ||||||
| All | AA | 27 (12.5) | 238 (16.8) | 1.41 (0.93–2.21) | 0.108 | 1.11 (0.82–1.49) | 0.514 | 1.15 (0.93–1.42) | 0.198 |
| AC | 108 (50.0) | 678 (47.8) | 1254.0 | 1256.2 | 1254.9 | ||||
| CC | 81 (37.5) | 504 (35.5) | |||||||
| Male | AA | 19 (14.4) | 157 (15.9) | 1.10 (0.67–1.90) | 0.709 | 1.06 (0.72–1.54) | 0.774 | 1.06 (0.81–1.38) | 0.691 |
| AC | 65 (49.2) | 484 (48.9) | 814.7 | 814.8 | 814.7 | ||||
| CC | 48 (36.4) | 348 (35.2) | |||||||
| Female | AA | 8 (9.5) | 81 (18.8) | 2.44 (1.17–5.77) | 0.016 | 1.26 (0.76–2.07) | 0.362 | 1.39 (0.98–2.00) | 0.063 |
| AC | 43 (51.2) | 194 (45.0) | 437.5 | 442.4 | 439.8 | ||||
| CC | 33 (39.3) | 156 (36.2) | |||||||
Adjusted by main sport (athletics), playing years, and competitive level. AIC, Akaike information criterion. Values in bold indicate P < 0.05.
*P value by logistic regression analysis.