TABLE 2.
Association of COL1A1 rs1107946 polymorphism with muscle injury in J-HAP (n = 1564).
| Genotype | n (%) | Dominant | Recessive | Additive | |||||
|---|---|---|---|---|---|---|---|---|---|
| Muscle Injury | No Muscle Injury | OR (95% CI) AIC | P* | OR (95% CI) AIC | P* | OR (95% CI) AIC | P* | ||
| rs1107946 | CC+ AC vs AA | CC vs AC + AA | CC vs AC vs AA | ||||||
| All | AA | 37 (19.4) | 223 (16.2) | 0.79 (0.54–1.19) | 0.261 | 0.92 (0.67–1.27) | 0.634 | 0.90 (0.73–1.12) | 0.352 |
| AC | 87 (45.6) | 652 (47.5) | 1130.4 | 1131.5 | 1130.8 | ||||
| CC | 67 (35.1) | 498 (36.3) | |||||||
| Male | AA | 21 (15.7) | 153 (16.4) | 1.04 (0.64–1.76) | 0.881 | 1.12 (0.77–1.63) | 0.551 | 1.07 (0.82–1.40) | 0.622 |
| AC | 61 (45.5) | 450 (48.3) | 795.5 | 795.1 | 795.3 | ||||
| CC | 52 (38.8) | 328 (35.2) | |||||||
| Female | AA | 16 (28.1) | 70 (15.8) | 0.46 (0.24–0.91) | 0.026 | 0.56 (0.29–1.04) | 0.067 | 0.61 (0.41–0.91) | 0.014 |
| AC | 26 (45.6) | 202 (45.7) | 341.9 | 343.5 | 340.8 | ||||
| CC | 15 (26.3) | 170 (38.5) | |||||||
Adjusted by main sport (athletics), playing years, and competitive level. AIC, Akaike information criterion. Values in bold indicate P < 0.05.
*P value by logistic regression analysis.