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. 2021 Jul 29;11:700947. doi: 10.3389/fonc.2021.700947

Figure 1.

Figure 1

Acetylation by HATs and deacetylation by HDACs influence gene transcriptional activity. HATs and HDACs add or remove acetyl groups at the N−terminus lysine, which leads to an open or condensed state of the chromatin.