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. 2021 Aug 4;2021:5527387. doi: 10.1155/2021/5527387

Figure 3.

Figure 3

Knockdown of PLEK2 significantly suppressed gastric cancer cell proliferation, colony formation, and migration. (a) The stable knockdown of PLEK2 in MGC803 and SGC7901 cells by shRNA sequences (shPLEK2). The knockdown effect was verified at the mRNA and protein levels. (b) PLEK2 knockdown significantly reduced the proliferation rate of MGC803 and SGC7901 cells. (c) The knockdown of PLEK2 impaired the colony formation ability of gastric cancer cells. (d) The knockdown of PLEK2 suppressed gastric cancer cell migration. (e) The knockdown of PLEK2 significantly reduced the wound healing ability of gastric cancer cells. ∗P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001 (t-test).