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. 2021 Jul 15;9(4):100387. doi: 10.1016/j.esxm.2021.100387

Table 2.

Results of the PTT as a concomitant treatment

Author/year n Type of therapy PTD average daily use (hours) PTD average duration (months) Gain in SPL (cm, p) Mean curvature ° (SD) Change in curvature (°, %)
Gallo/201923 1. 76
2. 45
3. 56
1. L-arginine and pentoxifylline
2. L-arginine, pentoxifylline and verapamil
3. L-arginine, pentoxifylline, verapamil and PTD
1. 0
2. 0
3. 2-8
6 1. -0.1
p=0.33
2. 0.1
p=0.37
3. 0.7
p=0.1
1. 24.2 (9)
2. 25.4 (16.8)
3. 34.3 (17.9)
1. 0.5 (2.1)
p=0.36
2. 1.3 (5.1)
p=0.34
3. 8.2 (23.9)
p=0.006
Fernández-Pascual/201927 1. 50
2. 94
1. CCH + PNT +PTD modelling, tadalafil, pentoxifylline
2. CCH +PTD
modelling, tadalafil, pentoxifylline
1. 6-8
2. 6-8
2 1. +0.3 (0.5); p<0.001
2. +0.1 (0.3); p<0.01
1. 55.3 (14.5)
2. 50.6 (15.7)
1. 19.2 (6.1)°,
36.2 (12.5)%
2. 12.7 (5.0)°,
28.1(14.5)%
Alom/201926 1. 52
2. 45
3. 16
1. CCH+ modelling
2. CCH modelling + PTD
3. CCH + modelling  + RestoreX
1. 0
2. 1,9
3. 0,9
6 1. -0.7
2. -0.4
3. +1.9
p=0.56 (group 2 vs group 1)
p <0.0001 (group 3 vs group 1)
p <0.001 (group 3 vs group 2)
median (IQR):
1. 60 (45-75)
2. 61.5 (45-75)
3. 65 (50-85)
1. 20,3 °, 31.2%
2. 19,2 °, 30.2%
3. 33,8 ° 49.4%
Ziegelmann/201712 1. 35
2. 16
1. CCH + modelling +PTD
2. CCH +modelling
1. 1.7
2. 0
6 1. +0.4; p=0.25
2. -0.35;
p=0.48
1. 67.4 (25.1)
2. 62.1 (24.9)
1. 19.6 (16.1)°,
32.6 (26.8) %
2. 23.6 (19.9)°,
27.5 (30.1) %
Yafi/201525 1. 78
2. 34
1. IFN a-2b
2. IFN a-2b + PTD
1. N/A
2. N/A
N/A 1. +1.3 (0.8)
2. +2.4 (0.9)
p=0.5567
(group 1 vs group 2)
1. 42.3 (20.8)
2. 42.2 (14.6)
1. 9.9 (11.8)
2. 8.1 (16.0)
p= 0.4894
(group 1 vs group 2)
Abern/201224 1. 39
2. 35
1. verapamil, PTD, oral pentoxifylline and L-arginine
2. verapamil, oral pentoxifylline and L-arginine
1. 3.3
2. 0
6 1. +0,3;
p = 0.06
2. -0,7;
p = 0.46
1. 44.4 (40.0–48.7)
2. 36.6 (33.5–39.7)
(95% CI)
1. 11 °
2. 15.1

SD = standard deviation; PTT = penile traction therapy; PTD = penile traction device; SPL = stretched penile length; CCH = collagenase clostridium histolyticum; PNT = percutaneous needle tunneling; IQR = interquartile range; IFN = interferon.