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. 2021 Aug 12;11:16439. doi: 10.1038/s41598-021-95999-0

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Mean ± SEM quasi-static (cycle 4) and dynamic (cycle 10) cycling data of the six dry powder surfactant preparations from the 1st series at captive bubble surfactometry. Formulations PL70[7:3]-SMB, PL80[7:3]-SMB and PL80[4:1]-SMB contained Super Mini-B (SMB) and formulations PL70[7:3]-KL4, PL80[7:3]-KL4 and PL80[4:1]-Kl4 contained KL4 as surfactant protein B (SP-B) peptide mimic. PL70 and PL80 stand for 70% and 80% phospholipids, [7:3] and [4:1] for DPPC:POPG ratios. Black bars depict minimum surface tension and gray bars maximum surface tension at quasi-static cycle 4 (left-sided figure) and dynamic cycle 10 (right-sided figure) (n = 3–4). *p = 0.04 vs PL80[4:1]-KL4; ^#p = 0.02 vs PL80[4:1]-KL4. See Table 1 for details on composition of the surfactants.