Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Aug 12;11:16439. doi: 10.1038/s41598-021-95999-0

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Mean ± SEM adsorption and area compression values of the four dry powder surfactant formulations from the 2nd series. Formulations contained 70% phospholipids with a DPPC:POPG ratio of 7:3, Super Mini-B (SMB) or B-YL as surfactant peptide and lactose or trehalose as excipient. Surfactant formulations were tested at baseline (0 month) and after 1 and 3 months of exposure to 40⁰C and 75% relative humidity (1 month and 3 months). The left-sided figure depicts initial adsorption (IA) and post-expansion adsorption (PEA) expressed as surface tension in mN/m. The right-sided figure shows % compression necessary to reach minimum surface tension during quasi-static (QS) and dynamic cycling (DC) at 0, 1 and 3 months of exposure to 40 °C and 75% relative humidity. *p < 0.001 for IA vs corresponding PEA values.; ^#p < 0.05 for QS 3 months of SMB: Lactose vs B-YL: Trehalose and SMB: Trehalose; ^▲p = 0.012 for QS 1 month of B-YL: Trehalose vs SMB: Trehalose; ^§p < 0.0001 for QS 1 month of SMB: Trehalose vs QS 3 months of SMB: Trehalose; ^¶p = 0.0254 for DC 0 month of B-YL: Lactose vs B-YL: Trehalose; ^†p < 0.004 for DC 1 month of SMB: Trehalose vs B-YL:T rehalose and SMB: Lactose; ^θp < 0.004 for DC 1 month vs DC 0 and 3 months of SMB-Trehalose. See Table 1 for details on composition of the surfactants.