Fig. 4.

Relationship between T-cell activation and CD26 expression in elite controllers and progressors. (A) Frequency of CD3⁺CD26⁺ T-cells, CD4⁺CD26⁺ T-cells and CD8⁺CD26⁺ T-cells were compared amongst HIV-1 uninfected healthy controls (HCs) (n = 5), elite controllers (ECs) (n = 5) and progressors (n = 6). Percentage of (B) CD3⁺CD26⁺HLA-DR⁺ T-cells, CD4⁺CD26⁺HLA-DR⁺ T-cells and CD8⁺CD26⁺HLA-DR⁺ T-cells were compared amongst HCs (n = 5), ECs (n = 5) and progressors (n = 6). Box-whisker plots depict the median (horizontal black line), 25th and 75th percentile (margins of the box) and the min and max (whiskers). Dots represent all individuals. Correlation analysis was performed with all samples (n = 16) between frequency of CD3⁺CD26⁺ T-cells and (C) CD3⁺HLA-DR⁺ T-cells and (D) CD3⁺CD38⁺ T-cells.