Table 2.
Safety and feasibility. NO = nitric oxide. NO2 = nitrogen dioxide. FiO2 = Fraction of inspired oxygen. RVSP = Right Ventricular Systolic Pressure. Ppm = parts per million. Min = minutes. Max = maximum value.
| Total number of treatments, No. | 217 | ||
|---|---|---|---|
| NO2 inhaled, ppm | 1.1 [0.98–1.14], Max = 1.47 | ||
| FiO2, % |
23 [21–30] |
||
| Concerns | |||
| Mask discomfort | 3 | ||
| Tingling of hands bilaterally | 1 | ||
| Nausea |
1 |
||
| Before Treatment | 15 min after NO initiation | 5 min after treatment ends | |
| sMethemoglobin, % | 0.5 [0.2–0.8] Max 2.3 |
1.8 [1.4–2.2] Max 4.7 |
1.6 [1.2–2.0] Max 3.5 |
| RVSP (mmHg) | 19.4 [15.4–23.5] | 17.9 [15.2–20.1] | 18.8 [16.6–21.9] |