Fig. 7.

IONzymes compromise the lipid envelope and neighboring proteins of IAVs through lipid peroxidation. (a, b) The level of lipid peroxidation (MDA detection) when liposomes were treated by IONzymes, (c) or when IAVs (H5N1 SY strain) were treated by IONzymes. (d) TEM image of IAVs treated by IONzymes (4 mg/mL). The left image: untreated IAVs. The asterisk: the destroyed lipid envelope of virion. Scale bar: 50 μm. (E) Western blot analysis of hemagglutinin, neuraminidase, matrix protein 1, and nucleoprotein protein of IAVs treated by IONzymes. Adapted from Ref. [84], under CC BY 4.0.