Table 1.
Patient and tumor characteristics
| PC (n = 1891) | No PC (n = 330) | P value | |
|---|---|---|---|
| (n, %) | (n, %) | ||
| Mean age (SD) | 72.1 (8.6) | 72.1 (8.6) | .96 |
| Sex | .38 | ||
| Male | 1841 (97.4) | 324 (98.2) | |
| Female | 50 (2.6) | 6 (1.8) | |
| Clinical T | < .0001 | ||
| T1 | 1444 (76.4) | 294 (89.1) | |
| T2a | 447 (23.6) | 36 (10.9) | |
| Histology | NA | ||
| Adenocarcinoma | 828 (43.5) | NA | |
| Squamous cell | 21 (1.1) | NA | |
| Mixed | 784 (41.5) | NA | |
| Large cell | 16 (0.9) | NA | |
| Other | 242 (12.8) | NA | |
| Grade | NA | ||
| 1 | 95 (5.0) | NA | |
| 2 | 281 (14.9) | NA | |
| 3-4 | 344 (18.1) | NA | |
| Unknown | 1171 (61.9) | NA | |
| Charlson index | .61 | ||
| 0 | 200 (10.6) | 30 (9.1) | |
| 1 | 719 (38.0) | 131 (39.7) | |
| 2 | 230 (12.2) | 35 (10.6) | |
| 3 | 387 (21.0) | 65 (19.7) | |
| ≥4 | 345 (18.2) | 69 (20.9) | |
| Smoking status | .18 | ||
| Current | 987 (52.2) | 171 (51.8) | |
| Former | 808 (42.7) | 151 (45.8) | |
| Never | 43 (2.3) | 3 (0.9) | |
| Unknown | 53 (2.8) | 5 (1.5) | |
| Histoplasmosis belt | < .0001 | ||
| Yes | 739 (39.1) | 89 (27.0) | |
| No | 1,152 (60.9) | 241 (73.0) | |
| Workup | |||
| PET | 1773 (93.8) | 315 (95.5) | 0.23 |
| Biopsy | NA | 134 (40.6) | NA |
| EBUS | 301 (15.9) | 42 (12.7) | 0.14 |
Abbreviations: EBUS = endobronchial ultrasound; PC = pathologic confirmation; PET = positron emission tomography; SD = standard deviation.
Histoplasmosis belt includes: Alabama, Arkansas, Iowa, Illinois, Indiana, Kansas, Kentucky, Maryland, Mississippi, Nebraska, Oklahoma, Tennessee, Texas, Virginia, West Virginia, Washington DC.1