Table 2.
Cox proportional hazards model for OS and LCSS
| OS |
LCSS |
|||||
|---|---|---|---|---|---|---|
| Characteristic | HR | 95% CI | P value | HR | 95% CI | P value |
| Age | 1.016 | (1.009, 1.023) | < .0001 | 1.003 | (0.994, 1.013) | .52 |
| Sex | ||||||
| Male | Ref | Ref | ||||
| Female | 0.73 | (0.49, 1.10) | .14 | 0.81 | (0.48, 1.36) | .42 |
| PC | ||||||
| No | Ref | Ref | ||||
| Yes | 1.1 | (0.93, 1.30) | .29 | 1.31 | (1.03, 1.67) | .031 |
| T stage | ||||||
| T1 | Ref | Ref | ||||
| T2a | 1.27 | (1.11, 1.45) | .0005 | 1.56 | (1.31, 1.85) | < .0001 |
| Smoking history | ||||||
| None | Ref | Ref | ||||
| Current | 0.99 | (0.68, 1.45) | .96 | 0.86 | (0.52, 1.44) | .57 |
| Previous | 0.95 | (0.65, 1.39) | .81 | 0.87 | (0.52, 1.44) | .58 |
| Charlson index | ||||||
| 0 | Ref | Ref | ||||
| 1 | 1.20 | (0.97, 1.49) | .097 | 1.19 | (0.90, 1.57) | .23 |
| 2 | 1.78 | (1.39, 2.27) | < .0001 | 1.48 | (1.07, 2.05) | .017 |
| 3 | 1.45 | (1.16, 1.81) | .0013 | 1.30 | (0.97, 1.74) | .08 |
| ≥4 | 1.76 | (1.40, 2.22) | < .0001 | 1.39 | (1.03, 1.88) | .033 |
| PET | ||||||
| No | Ref | Ref | ||||
| Yes | 0.80 | (0.64, 1.02) | .067 | 0.69 | (0.51, 0.93) | .016 |
| EBUS | ||||||
| No | Ref | Ref | ||||
| Yes | 0.94 | (0.79, 1.11) | .46 | 0.90 | (0.71, 1.13) | .36 |
| Histoplasmosis belt | ||||||
| No | Ref | Ref | ||||
| Yes | 1.00 | (0.89, 1.13) | .98 | 0.91 | (0.77, 1.06) | .22 |
| Facility complexity | ||||||
| 1a | Ref | Ref | ||||
| 1b | 0.98 | (0.84, 1.15) | .83 | 1.06 | (0.86, 1.29) | .60 |
| 1c | 0.99 | (0.85, 1.14) | .86 | 0.94 | (0.76, 1.15) | .52 |
| 2 | 1.11 | (0.89, 1.38) | .34 | 1.07 | (0.81, 1.41) | .64 |
| 3 | 1.34 | (0.88, 2.05) | .17 | 1.70 | (1.04, 2.77) | .034 |
| Primary insurance | ||||||
| VA/military/Tricare | Ref | Ref | ||||
| Medicare/Medicaid | 1.11 | (0.98, 1.26) | .10 | 1.15 | (0.97, 1.36) | .098 |
| Private | 0.97 | (0.53, 1.77) | .92 | 0.51 | (0.20, 1.30) | .16 |
| Uninsured | 1.18 | (0.49, 2.86) | .72 | 0.69 | (0.15, 3.09) | .63 |
| Treatment year | ||||||
| 2008 | Ref | Ref | ||||
| 2009 | 0.940 | (0.72, 1.23) | .6490 | 1.071 | (0.74, 1.54) | .7102 |
| 2010 | 0.962 | (0.74, 1.26) | .7760 | 1.150 | (0.81, 1.64) | .4359 |
| 2011 | 1.006 | (0.78, 1.23) | .9614 | 1.003 | (0.71, 1.41) | .9879 |
| 2012 | 0.879 | (0.68, 1.13) | .3177 | 0.880 | (0.62, 1.24) | .4690 |
| 2013 | 1.011 | (0.78, 1.31) | .9333 | 0.985 | (0.70, 1.39) | .9337 |
| 2014 | 0.879 | (0.68, 1.14) | .3382 | 0.898 | (0.63, 1.28) | .5495 |
| 2015 | 0.899 | (0.67, 1.21) | .4836 | 0.884 | (0.59, 1.32) | .5530 |
Abbreviations: CI = confidence interval; EBUS = endobronchial ultrasound; HR = hazard ratio; LCSS = lung cancer specific survival; OS = overall survival; PC = pathologic confirmation; PET = positron emission tomography; VA = Veterans Affairs.