Table 3.
Estimates obtained from least absolute shrinkage and selection operator (Lasso) regression analyses showing the prediction models of acute postsurgical pain. (N = 1,579) Independent variables are the preoperative predictors. The dependent variables are movement-evoked acute postsurgical pain (NRS-MEP) at day 1, 2, 3 and over the first three days after surgery.
| Preoperative predictors | Day 1 | Day 2 | Day 3 | Day 123 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Est | RMSE | R2 | Est | RMSE | R2 | Est | RMSE | R2 | Est | RMSE | R2 | |
| 2.52 | 0.162 | 2.44 | 0.163 | 2.18 | 0.176 | 2.11 | 0.207 | |||||
| Intercept | 4.082 | 3.564 | 3.099 | 3.669 | ||||||||
| Hospital admittance | 0.018 | 0.087 | 0.091 | |||||||||
| Female sex | 0.101 | 0.019 | ||||||||||
| Preoperative movement evoked pain | 0.148 | 0.130 | 0.148 | 0.146 | ||||||||
| Age | − 0.017 | − 0.016 | − 0.017 | − 0.021 | ||||||||
| PCS total | 0.010 | 0.019 | 0.014 | 0.015 | ||||||||
| APAIS anxiety | 0.051 | 0.028 | 0.041 | 0.047 | ||||||||
| PDI total | 0.012 | 0.011 | 0.008 | 0.012 | ||||||||
| Category expected pain | ||||||||||||
| Category expected pain 1 | ||||||||||||
| Category expected pain 2 | ||||||||||||
| Category expected pain 3 | ||||||||||||
| Category expected pain 4 | 0.094 | |||||||||||
| Category expected pain 5 | 0.138 | 0.286 | 0.161 | 0.272 | ||||||||
| Medical specialty | ||||||||||||
| General surgery | ||||||||||||
| Orthopedics | ||||||||||||
| Urology | 0.053 | |||||||||||
| Gynecology | ||||||||||||
| ENT | − 0.157 | − 0.087 | ||||||||||
| Eye surgery | ||||||||||||
| Plastic surgery | ||||||||||||
| Neurosurgery | ||||||||||||
| Oro-maxillofacial surgery | ||||||||||||
| Other surgeries | ||||||||||||
| Wound size unknown* | 0.187 | |||||||||||
| Wound size > 10 cm* | 0.197 | 0.170 | 0.265 | |||||||||
Est means estimate; RMSE means Root Mean Square Error; R2 means R-squared; PCS means Pain Catastrophizing Scale; APAIS means Amsterdam Pain Anxiety and Information Scale; PDI means Pain Disability Index. Meaningful predictors in one of the four prediction models are displayed in bold font.
* compared to wound size ≤ 10 cm.