Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Aug 12;12:4877. doi: 10.1038/s41467-021-25181-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 3 — a QPCR analysis of GLIS1 and MYOC mRNA expression in human TM tissue, kidney (Ki), and liver (Li) (n = 3; technical replicates). Statistical analyses were performed with a two-tailed Student’s t test. Data are represented as means ± SD. p Values are indicated above the bars. b Comparison of mouse GLIS1 RNA expression in several ocular tissues with that of kidney, a tissue in which GLIS1 is highly expressed (n = 3; distinct samples). Statistical analyses were done with a two-tailed Student’s t test. Data are represented as means ± SD. p Values are indicated above the bars. c RNAscope in situ hybridization with eye sections from a 3-month-old WT mouse showed that GLIS1 mRNA (yellow speckles) expression was restricted to TM and CB. Dashed lines outline different cell compartments. Kidney (Ki), Cornea (C), Retina (R), Ciliary Body (CB), Trabecular Meshwork (TM), Corneal StromaI (CS), Iris (I), and Schlemm’s canal (SC). Scale bar = 50 μm.