Fig. 3. Using single-cell transcriptome data to improve the comparative annotation of plant genomes.

Expression profiles across multiple cell types derived from single-cell transcriptome data of tissues from different plant species (left), in combination with sequence homology-based comparison of protein sequences (top right), can be used to identify functionally homologous genes across different plant species (bottom right), thereby substantially enhancing the ability to assign functional knowledge from deeply annotated model species correctly to other species that are of interest to bioenergy and biomaterial production.