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. 2021 Aug 12;6:101. doi: 10.1038/s41541-021-00366-9

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — The concentration of a monoclonal antibody (mAb) 4B7 (Pfs25), b mAb 45.1 (Pfs48/45) and (c) mAb 2A2 (Pfs230) in the feeder is indicated below bars. Transmission-reducing activity (TRA) was quantified as the reduction in mean oocyst intensity between antibody control and mAb condition for each donor. Complete transmission-reducing (>99% TRA) is depicted in dark green and strong reduction (80–99% TRA) in bright green. All donors with >1 oocyst/mosquito in antibody control condition (i.e. successful transmission) were included and the number of distinct donor samples (n) tested for each antibody is given below bars. mAbs 4B7 and 45.1 were tested at two sites (Burkina Faso and Cameroon) and mAb 2A2 was only tested in Burkina Faso. DMFA direct membrane feeding assays. The raw data for DMFA and SMFA experiments can be found in the Supplementary Material (Supplementary Dataset 1 and 2).