Table 1.

Secondary Outcomes

Outcome
Time to clinical resolution of infection (defined as number of days from randomization to resolution of fever [temperature <38°C])
Clinical and microbiological success at day 5 (defined as survival plus resolution of fever and leukocytosis [white blood cell count <12 × 109/L])
Length of hospital or intensive care unit stay
Requirement of intensive care unit admission
Infection with piperacillin-tazobactam or carbapenem-resistant organisms or Clostridioides difficile
Microbiological failure with third-generation cephalosporin-resistant isolate (same species as index blood culture isolated) in a subsequent sterile site
Colonization with multidrug-resistant organism(s)
Requirement of escalation of antibiotic therapy