Table 4.
Effect of dihydroartemisinin (DHA) on enterocyte proliferation and apoptosis in weaned piglets with intrauterine growth retardation (IUGR).
| Item | Treatment1 |
P-value |
|||
|---|---|---|---|---|---|
| NBW-CON | IUGR-CON | IUGR-DHA | NBW-CON vs. IUGR-CON | IUGR-CON vs. IUGR-DHA | |
| Jejunum | |||||
| AI, % | 3.80 ± 0.25 | 9.72 ± 0.42∗ | 6.62 ± 0.15# | <0.001 | <0.001 |
| PI, % | 21.44 ± 1.22 | 15.07 ± 0.60∗ | 20.08 ± 0.89# | 0.001 | 0.005 |
| Ileum | |||||
| AI, % | 4.05 ± 0.24 | 7.13 ± 0.25∗ | 5.31 ± 0.30# | <0.001 | 0.001 |
| PI, % | 30.10 ± 1.11 | 18.18 ± 1.03∗ | 28.42 ± 1.41# | <0.001 | <0.001 |
AI = apoptosis index; PI = proliferation index.
∗, a significant difference (P < 0.05) between NBW-CON group and IUGR-CON group; #, a significant difference (P < 0.05) between IUGR-DHA group and IUGR-CON group.
1
NBW-CON, normal body weight group fed a basal diet; IUGR-CON, IUGR group fed a basal diet; IUGR-DHA, IUGR group fed a DHA-supplemented diet at 80 mg/kg. Results were showed as means ± SEM (n = 8).