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. 2021 Aug 13;39:101086. doi: 10.1016/j.eclinm.2021.101086

Table 2.

Immune recovery of Lymphocytes, CD3+, CD4+, CD8+, CD56+, CD19+ cells and NKTsubpopulations after infusion of CD45RA- memory T cells. Data is shown as median, [IQR] N/D: N/D Not Determined not data; Pre: Pre infusion.

Dose 1 × 105 cells/kg
Low dose
5 × 105 cells/kg
Medium dose
1 × 106 cells/kg
High dose
Variable
Lymphocytex109/L (median [IQR])
Pre 0.79 [0.72] 1.33 [0.75] 1.01 [0.65]
Week 1 1.76 [1.48] 2.02 [2.57] 1.77 [2.03]
Week 2 2.19 [0.45] 2.40 1.87
CD3+ cells x109/L (median [IQR])
Pre N/D 0.85 [0.57] 0.77 [0.26]
Week 1 1.11 [0.26] 1.34 [2.06] 1.32 [1.44]
Week 2 1.68 [0.27] 1.54 1.51
CD4+ cells x109/L (median [IQR])
Pre N/D 0.61 [0.42] 0.61 [0.51]
Week 1 0.68 [0.20] 1.04 [1.5] 1.16 [1.25]
Week 2 0.77 [0.28] 1.21 1.21
CD8+ cells x109/L (median [IQR])
Pre N/D 0.13 [0.08] 0.15 [0.24]
Week 1 0.32 [0.12] 0.26 [0.44] 0.21 [0.28]
Week 2 0.81 [0.69] 0.26 0.32
NK cells x109/L (median [IQR])
Pre N/D 0.27 [0.13] 0.24 [0.33]
Week 1 0.14 [0.06] 0.13 [0.21] 0.21 [0.57]
Week 2 0.27 [0.15] 0.15 0.18
B cells x109/L (median [IQR])
Pre N/D 0.07 [0.20] 0.07 [0.16]
Week 1 0.49 [0.30] 0.31 [0.59] 0.31 [0.25]
Week 2 0.27 [0.06] 0.71 0.17
NKT (%) (median [IQR])
Pre N/D 2.90 [8.70] 1.20 [6.60]
Week 1 2.50 [5.40] 1.70 [1.20] 0.70 [4.50]
Week 2 6.80 [16.60] 4.30 1.8