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. 2021 Aug 13;39:101086. doi: 10.1016/j.eclinm.2021.101086

Table 4.

Donor chimerism after infusion of CD45RA- memory T cells from the convalescent donor. The indicated chimerism values were obtained as the mean value of the analysis of two different INDEL systems. Pre-infusion patient samples were analysed, and results were employed as negative background control. The data are shown by weeks after infusion.

Dose cohort
Variables 1 × 105 cells/kg
5 × 105 cells/kg
1 × 106 cells/kg
Donor Chimerism (%) #1 #2 #3 #4 #5 #6 #7 #8 #9
D0-D7 0.011 1.445 0.405 0.065 0.023 0.192 0.989 0.450 <0.01
D7-D14 <0.01 0.310 <0.01 0.097 0.185 0.086 3.090 0.163 0
D14–21 0.084 0.163 <0.01 0.135 <0.01 <0.01 <0.01 <0.01 0.2
D21–28 N/D N/D N/D N/D N/D N/D N/D N/D 0.011