Table 3.
Cortisol partial correlations in the MDD group.
| Structure |
T0 min |
T30 min |
T60 min |
AUCg |
|---|---|---|---|---|
| Nucleus/Composite measure | p-uncorrected, value (r-statistic) | |||
| LEFT | ||||
| Lateral | 0.507 (−0.136) | 0.024 (−0.441) | 0.025 (−0.437) | 0.015 (−0.474) |
| Basal | 0.953 (−0.012) | 0.198 (−0.261) | 0.127 (−0.307) | 0.104 (−0.326) |
| Acc basal | 0.656 (−0.092) | 0.936 (0.017) | 0.459 (−0.152) | 0.29 (−0.216) |
| AAA | 0.407 (−0.173) | 0.072 (−0.366) | 0.076 (−0.362) | 0.069 (−0.37) |
| Central | 0.897 (−0.027) | 0.899 (0.027) | 0.611 (0.107) | 0.536 (0.13) |
| Medial | 0.767 (−0.064) | 0.476 (0.153) | 0.571 (0.122) | 0.91 (−0.024) |
| Cortical | 0.999 (0) | 0.434 (0.164) | 0.992 (0.002) | 0.857 (−0.038) |
| CATA | 0.006 (−0.524) | 0.03 (−0.426) | 0.000130 (−0.681) | 0.00003 (−0.72) |
| Paralaminar | 0.958 (0.011) | 0.415 (−0.167) | 0.346 (−0.193) | 0.336 (−0.197) |
| Whole amygdala | 0.469 (−0.148) | 0.115 (−0.317) | 0.04 (−0.405) | 0.022 (−0.446) |
| Laterobasal | 0.645 (−0.095) | 0.096 (−0.333) | 0.055 (−0.38) | 0.033 (−0.419) |
| Centromedial | 0.854 (−0.039) | 0.456 (0.156) | 0.515 (0.136) | 0.675 (0.088) |
| Superficial | 0.045 (−0.396) | 0.07 (−0.361) | 0.002 (−0.579) | 0.001 (−0.624) |
| RIGHT | ||||
| Lateral | 0.388 (−0.18) | 0.353 (−0.194) | 0.321 (−0.207) | 0.356 (−0.193) |
| Basal | 0.259 (−0.23) | 0.055 (−0.381) | 0.093 (−0.336) | 0.1 (−0.33) |
| Acc basal | 0.141 (−0.297) | 0.168 (−0.279) | 0.328 (−0.2) | 0.145 (−0.294) |
| AAA | 0.828 (−0.045) | 0.398 (−0.173) | 0.984 (−0.004) | 0.671 (0.088) |
| Central | 0.848 (0.04) | 0.755 (0.064) | 0.601 (0.108) | 0.484 (0.144) |
| Medial | 0.21 (0.254) | 0.132 (0.304) | 0.014 (0.477) | 0.083 (0.347) |
| Cortical | 0.994 (−0.001) | 0.896 (−0.027) | 0.874 (−0.033) | 0.624 (−0.101) |
| CATA | 0.031 (−0.424) | 0.026 (−0.437) | 0.025 (−0.44) | 0.005 (−0.538) |
| Paralaminar | 0.318 (−0.204) | 0.098 (−0.332) | 0.097 (−0.333) | 0.169 (−0.278) |
| Whole amygdala | 0.374 (−0.186) | 0.336 (−0.201) | 0.395 (−0.178) | 0.357 (−0.192) |
| Laterobasal | 0.336 (−0.201) | 0.266 (−0.231) | 0.281 (−0.224) | 0.271 (−0.229) |
| Centromedial | 0.49 (0.142) | 0.36 (0.187) | 0.14 (0.297) | 0.196 (0.262) |
| Superficial | 0.116 (−0.316) | 0.054 (−0.383) | 0.116 (−0.316) | 0.067 (−0.364) |
Salivary cortisol was measured at 0, 30 and 60 min after waking. The cortisol awakening response was calculated using the area under the curve with respect to ground (AUCg). The FDR based threshold for significance was p ≤ 0.0003, marked in bold text. Italic text denotes p-values ≤ 0.05 but not surviving the FDR threshold. AAA, anterior amygdalar area; AUCg, area under the curve with respect to ground; CATA, cortical amygdalar transition area; FDR, false discovery rate; MDD, major depressive disorder.