Figure 1.

Clonal hematopoiesis in CAR T-cell cohort. (A) The frequency of CH stratified by the size of the clone, as measured by the variant allele fraction across the entire cohort (All) and within particular age groups. (B) The number of mutations (y-axis) identified in each gene (x-axis) at differing VAF across the entire cohort. (C) Progression-free survival of patients with non-Hodgkin lymphoma stratified by absence (red) or presence (orange) of clonal hematopoiesis with a VAF ≥0.02. A log-rank test was performed to compare survival curves. (D) Overall survival of patients with non-Hodgkin lymphoma stratified by absence (red) or presence (orange) of clonal hematopoiesis with a VAF ≥0.02. A log-rank test was performed to compare survival curves.