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. 2021 Jul 30;12:697483. doi: 10.3389/fphar.2021.697483

FIGURE 1.

FIGURE 1

OA improves glucose and lipid metabolism and alleviates diet-induced IR. (A) Body weight of mice in vehicle, 25 mg/kg OA, 50 mg/kg OA group at the end of the experiment (n = 7). (B) Glucose tolerance test (GTT) in mice after 4 weeks of OA treatment (n = 7). (C) Fasting plasma insulin levels (n = 7). (D) HOMA-IR index (n = 7). (E) Western blots of phospho-Ser473 Akt (p-Akt), and Akt in eWAT of mice. (F) Plasma concentrations of triglyceride, total cholesterol, FFA at baseline (fasted), and Adipo-IR index (n = 5–7). (G) Western blots of phospho-Ser660 HSL (p-HSL), and HSL in the eWAT of mice. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.