Table 5.

Properties of the identified allergenic proteins following direct antibody treatment (DAT) and direct microglia treatment (DMT) on the mouse primary neuron (MPN) cells in comparison with untreated cells.

Accession	Gene ID	Description	Peptides	Unique peptides	Confidence score	Anova (p)	Max fold change	Highest Mean	Lowest Mean
Direct Antibody Treatment (DAT)
A0A0R4J0A4	Flt1	Vascular endothelial growth factor receptor 1	4	4	15.6	7.59E-05	5.69	NOT	DAT
B1AXW5	Prdx1	Peroxiredoxin-1 (Fragment)	8	6	60.2	9.35E-05	2.44	NOT	DAT
A0A571BEW5	Lpar2	Lysophosphatidic acid receptor 2	3	2	19.3	0.000114	10.6	DAT	NOT
P63038	Hspd1	60 kDa heat shock protein_ mitochondrial	48	43	479	0.008456	1.76	DAT	NOT
F6Q404	Pdia3	Protein disulfide-isomerase A3 (Fragment)	6	1	34.6	0.00903	1.79	NOT	DAT
Q3TCI7	Ldha	L-lactate dehydrogenase	15	4	126	0.011567	3.83	NOT	DAT
Q91Y50	Il4	Interleukin-4	3	1	27	0.015679	2.02	NOT	DAT
S4R2M7	Pgk1	Phosphoglycerate kinase	12	1	115	0.018003	1.54	DAT	NOT
A0A3B2W7W2	Ppard	Peroxisome proliferator-activated receptor delta	19	17	121	0.036966	1.43	DAT	NOT
Q3UBP6	Actb	Uncharacterized protein	36	4	356	0.040245	1.39	DAT	NOT
Direct Microglia Treatment (DMT)
A0A0R4J0A4	Flt1	Vascular endothelial growth factor receptor 1	4	4	15.6	8.51E-05	10.3	NOT	DMT
Q3TD08	Ndrg1	Uncharacterized protein	6	6	32	0.001982	2.86	DMT	NOT
Q78NA6	Rag1	V(D)J recombination-activating protein 1	5	3	22.3	0.002166	2.98	NOT	DMT
Q61916	Muc5ac	Mucin (Fragment)	3	1	24.4	0.013162	1.5	DMT	NOT
A0A571BEW5	Lpar2	Lysophosphatidic acid receptor 2	3	2	19.3	0.013879	2.94	DMT	NOT
Q3UBS0	Apoe	Uncharacterized protein	7	5	38.8	0.015268	2.15	NOT	DMT
Q99LX0	Park7	Protein/nucleic acid deglycase DJ-1	7	7	58.3	0.044158	1.36	NOT	DMT

The properties were identified by Progenesis Software after the LC-MS analysis.