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. 2021 Jul 30;8:692120. doi: 10.3389/fmolb.2021.692120

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Copyright © 2021 Liu, Xue, Zhong, Wang, Li and Zhu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The prognostic impact of COL1A1 in 33 types of human tumors were examined using GEPIA2. (A) High expression of COL1A1 was associated with poor overall survival in KIRP (HR = 2.2, p = 0.011), LGG (HR = 2, p = 0.00028), MESO (HR = 2.2, p = 0.0014), SKCM (HR = 1.5, p = 0.0032), and STAD (HR = 1.5, p = 0.013). (B) High expression of COL1A1 was associated with poor disease-free survival in CESC (HR = 2, p = 0.018), COAD (HR = 1.6, p = 0.041), ESCA (HR = 1.6, p = 0.045), KIRP (HR = 3.1, p < 0.001), LGG (HR = 1.4, p = 0.024), and PRAD (HR = 2, p = 0.0011).