Table 6.
Previous Studies That Examined the Effect of RT on Primary TC.
| Author | Year | Patients, n (PORT/DRT) |
Histology SCC/ACC |
Dose (Gy) PORT/DRT |
CR, % | Survival |
|---|---|---|---|---|---|---|
| Fields4 | 1989 | 24 (6/18) | 13/4 | <40-70 | 86(6/7) | 5-year OS: 25% |
| Makarewicz5 | 1998 | 23 (NP/8) | 13/7 | >60 | 75 | Mean survival: 26 months |
| Chao6 | 1998 | 42 (9/32) | 28/3 | 10-64 | 50 (4/8) | Median survival: 5.7 months |
| Bhattacharyya3 | 2004 | 92 (39/21) | 41/19 | NP | NP | Mean survival: 63.3 months |
| Webb8 | 2006 | 45 (10/18) | 26/7 | 29.8-70/18-130 | NP | 5-year DSM: 72.9% |
| Honing16 | 2007 | 293 (23/156) | 156/21 | NP | NP | 5-year OS: 15% |
| Xie9 | 2012 | 78 (46/30) | 33/12 | NP | NP | 5-year OS: 42.3% |
| Je11 | 2017 | 22 (13/9) | All ACC | 50.4/60-66 | 11.1 (1/9) | 5-year OS: 81.8% |
| Levy10 | 2018 | 31 (22/9) | All ACC | 45-65/66-70 | NP | 5-year OS: 88% |
Abbreviations: PORT, post-operative radiotherapy; DRT, definitive radiotherapy; SCC, squamous cell carcinoma; ACC, adenoid cystic carcinoma; CR, complete remission; DSM, disease-specific mortality; NP, not provided.