Table 3.
Association of peripheral inflammatory cytokines and Alzheimer’s disease risk
| Cytokines | Number of subjects | Mean | Median | P valuea | ||
|---|---|---|---|---|---|---|
| AD/NC | AD | NC | AD | NC | ||
| IL-6 | 18/41 | 3.57 | 2.75 | 1.44 | 1.63 | 0.792 |
| IL-8 | 18/43 | 7.38 | 6.77 | 6.09 | 5.99 | 0.794 |
| IL-10 | 18/43 | 1.08 | 1.85 | 1.01 | 1.18 | 0.315 |
| G-CSF | 19/43 | 1.28 | 1.84 | 1.27 | 1.59 | 0.008 |
| IL-7 | 19/43 | 2.14 | 2.22 | 2.05 | 2.05 | 0.667 |
| IL-8 | 19/43 | 3.17 | 3.29 | 2.40 | 3.15 | 0.113 |
| IL-12 | 19/42 | 1.32 | 1.50 | 0.95 | 0.95 | 0.849 |
| IFN-γ | 19/42 | 0.97 | 1.75 | 0.66 | 1.40 | 0.007 |
| MCP-1 | 19/43 | 6.87 | 8.27 | 6.85 | 7.72 | 0.172 |
| MIP-1β | 19/43 | 8.33 | 10.95 | 6.45 | 8.28 | 0.194 |
| TNF-α | 19/39 | 2.27 | 2.67 | 1.61 | 2.12 | 0.314 |
AD Alzheimer’s disease, NC cognitively normal control
a Comparison between AD group and NC group of median, using Mann-Whitney U test