Table 1.
Variables | Mild steatosis (N = 111) | Moderate steatosis (N = 16) | Severe steatosis (N = 10) | Nonsteatosis (N = 223) | P |
---|---|---|---|---|---|
Preoperative donor parameters | |||||
Donor age, years | 40.03 ± 1.03 | 38.38 ± 3.28 | 41.30 ± 5.06 | 37.29 ± 0.88 | 0.254 |
Donor sex male n (%) | 89 | 15 | 10 | 173 | 0.162 |
Donor type | |||||
DBD | 102 | 15 | 10 | 205 | 0.972 |
DCD | 8 | 1 | 0 | 17 | |
DBCD | 1 | 0 | 0 | 1 | |
BMI (kg/m2) | 22.17 ± 0.30 | 21.03 ± 0.95 | 20.95 ± 0.76 | 22.37 ± 0.22 | 0.250 |
Cause of death | |||||
Anoxia | 7 | 0 | 1 | 13 | 0.534 |
Trauma | 53 | 11 | 7 | 126 | |
Vascular | 49 | 5 | 2 | 76 | |
Other | 2 | 0 | 0 | 8 | |
AST (U/l) | 150.76 ± 24.50 | 84.56 ± 27.27 | 142.00 ± 21.29 | 107.30 ± 10.65 | 0.215 |
ALT (U/l) | 77.88 ± 8.36 | 47.50 ± 9.22 | 90.50 ± 21.18 | 79.12 ± 6.68 | 0.589 |
GGT (U/l) | 85.76 ± 10.02 | 74.25 ± 20.14 | 76.60 ± 29.26 | 86.88 ± 7.48 | 0.963 |
Bilirubin (mmol/l) | 24.41 ± 1.63 | 22.08 ± 3.03 | 31.28 ± 7.79 | 27.27 ± 1.74 | 0.544 |
CIT, h | 5.79 ± 0.3 | 5.50 ± 0.96 | 5.10 ± 1.22 | 5.99 ± 0.31 | 0.877 |
Donor WIT, min | 1.17 ± 0.49 | 1.25 ± 0.69 | 0 | 0.62 ± 0.12 | 0.387 |
ICG test result % | 4.77% ± 0.64% | 4.20% ± 2.0% | 3.52% ± 0.97% | 4.21% ± 0.41% | 0.882 |
Preoperative recipient parameters | |||||
Recipient age, years | 49.22 ± 1.12 | 53.56 ± 2.70 | 51.00 ± 2.50 | 60.67 ± 0.75 | 0.450 |
Recipient sex male n (%) | 103 | 15 | 10 | 200 | 0.560 |
BMI (kg/m2) | 23.37 ± 0.34 | 21.18 ± 0.90 | 21.73 ± 1.14 | 22.94 ± 0.25 | 0.101 |
MELD | 18.58 ± 0.87 | 16.56 ± 2.33 | 19.30 ± 3.06 | 19.34 ± 0.71 | 0.708 |
Diagnosis | |||||
HCC | 64 | 9 | 3 | 121 | 0.330 |
Cirrhotic | 31 | 6 | 7 | 68 | |
Acute liver failure | 5 | 1 | 0 | 14 | |
Others | 11 | 0 | 0 | 20 | |
Transplantation parameters | |||||
Anhepatic time, min | 55.06 ± 1.98 | 56.25 ± 5.58 | 60.50 ± 6.75 | 53.56 ± 1.29 | 0.661 |
Intraoperative transfusions (U) | 6.31 ± 0.53 | 7.40 ± 1.84 | 8.23 ± 2.56 | 7.31 ± 0.53 | 0.637 |
Blood loss (ml) | 2030.54 ± 165.96 | 3150.00 ± 842.12 | 2280.00 ± 254.65 | 2346.32 ± 184.23 | 0.351 |
Type of vena cava anastomosis | |||||
Classic | 52 | 5 | 3 | 90 | 0.821 |
Classic piggyback | 8 | 2 | 1 | 21 | |
Modified piggyback | 51 | 9 | 6 | 112 | |
ICU length‐of‐stay (h) | 83.44 ± 12.66 | 43.28 ± 8.70 | 111.90 ± 73.70 | 73.31 ± 7.74 | 0.477 |
Postoperative outcome parameters | |||||
EAD | 33 | 7 | 5 | 22 | <0.001 |
PNF | 1 | 0 | 2 | 1 | <0.001 |
Biliary anastomotic strictures | 2 | 0 | 0 | 2 | 0.833 |
Biliary leakage | 1 | 0 | 0 | 2 | 0.972 |
Hepatic artery complications | 2 | 0 | 0 | 5 | 0.889 |
Retransplantation | 1 | 0 | 0 | 2 | 0.972 |
ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; CIT, cold ischaemia time; DBCD, Donor after brain and cardiac death; DBD, donor after brain death; DCD, donor after cardiac death; EAD, early allograft dysfunction; GGT, γ‐glutamyl transpeptidase; HCC, hepatocellular carcinoma; ICG, indocyanine green; ICU, intensive care unit; IFLT, ischaemia‐free liver transplantation; MELD, model for end‐stage liver diseases; PNF, Primary nonfunction; WIT, warm ischaemia time.