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. 2021 Aug 13;16:56. doi: 10.1186/s13027-021-00397-w

Fig. 1.

Fig. 1

HPV16 E6 regulated the expression of DGCR8 in HNSCC cells. a The relative mRNA expression level of HPV16 E6 in E6-overexpressing/knockdown HNSCC cell lines. b The relative protein expression level of HPV E6 and DGCR8 in E6-overexpressing/knockdown HNSCC cell lines. c The relative mRNA expression level of DGCR8 in E6-overexpressing/knockdown HNSCC cell lines. d, e The relative expression level of miR-27a-3p in E6-overexpressing/knockdown HNSCC cell lines. f The expression sites of DGCR8 in E6-overexpressing HNSCC cell lines were observed by immunofluorescence. Original magnification ×200. Data were presented as mean ± SD. *P < 0.05; **P < 0.01; ***P < 0.001