Table 2.
Groups/ | TBARS | O 2 − (nmol/ml) | NO 2 − (nmol/ml) | H2O2(nmol/ml) |
---|---|---|---|---|
parameters | (μmol/ml) | |||
Sham | ||||
S | 17.4 ± 1.2f−i | 34.2 ± 1.1 | 87.7 ± 10.1 | 45.3 ± 1.1 |
1 | 18.3 ± 1.1f−i | 30.1 ± 2.1f−i | 85.4 ± 11.2 | 43.2 ± 1.6f−i |
7 | 17.1 ± 0.5f−i | 32.4 ± 4.1f−i | 83.2 ± 9.8 | 43.5 ± 3.2f−i |
I/R | ||||
S | 25.7 ± 1.3f | 95.2 ± 13.4 | 38.6 ± 1.2 | 48.7 ± 1.2 |
1 | 28.9 ± 1.2f | 97.8 ± 10.2f | 43.1 ± 1.2f | 49.3 ± 4.5f |
7 | 34.5 ± 2.4a,f | 108.1 ± 9.8a,b,f | 52.6 ± 4.4a,b,f | 55.4 ± 1.88a,b,f |
AUE125 | ||||
S | 22.9 ± 1.11g | 88.4 ± 1.6 | 41.2 ± 5.6 | 46.2 ± 1.2 |
1 | 23.4 ± 1.19c,g* | 92.1 ± 2.4g | 42.4 ± 4.8 | 53.2 ± 4.5ag |
7 | 26.7 ± 3.7a,d,g* | 92.3 ± 3.7g* | 42.7 ± 2.8g* | 48.4 ± 4.8g* |
AUE250 | ||||
S | 23.7 ± 1.4h | 86.9 ± 3.5* | 43.3 ± 2.6 | 51.2 ± 4.2 |
1 | 26.3 ± 2.7c,e,h | 91.3 ± 2.2h | 45.6 ± 3.8 | 53.4 ± 6.6h |
7 | 24.9 ± 1.9h* | 83.9 ± 3.9h* | 42.8 ± 2.7* | 50.9 ± 3.9h |
AUE500 | ||||
S | 21.2 ± 1.7i | 85.3 ± 5.4 | 42.5 ± 5.9 | 50.8 ± 1.5 |
1 | 23.4 ± 2.6e,i | 91.2 ± 3.9i | 45.6 ± 2.9 | 52.3 ± 6.7i |
7 | 22.9 ± 2.9d,i* | 86.9 ± 6.7i* | 41.9 ± 3.2* | 49.9 ± 2.3i |
Mean values ± SE in three points of interest. S, stabilization; 1, first minute of reperfusion; 7, 30th min of reperfusion;
Statistically significant difference at the level of p < 0.05 between the group I/R and AUE groups at the point of interest;
Statistically significant difference at the level of p < 0.05 in relation to point S within the group;
Statistically significant difference at the level of p < 0.05 in relation to the point 1 within the group;
Statistically significant difference at the level of p < 0.05 between AUE125 and AUE250;
Statistically significant difference at the level of p < 0.05 between AUE125 and AUE500;
Statistically significant difference at the level of p < 0.05 between AUE250 and AUE500
Statistically significant difference at the level of p < 0.05 between sham and I/R;
Statistically significant difference at the level of p < 0.05 between sham and AUE125;
Statistically significant difference at the level of p < 0.05 between sham and 250AUE;
Statistically significant difference at the level of p < 0.05 between sham and AUE500.