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. 2021 Jul 29;6:93. Originally published 2021 Apr 29. [Version 2] doi: 10.12688/wellcomeopenres.16594.2

Table 5. Summary of RAS to any DAA genotype in 1b by time point.

Baseline Post failure
Resistance to NS5a inhibitors N=13 N=2
30: R30Q 1 (8%) -
31: L31I 1 (8%) -
      L31M 1 (8%) -
37: L37I 1 (8%) -
54: Q54H 11 (84%) 2 (100%)
58: P58S 1 (8%) -
Resistance to NS5b inhibitors N=10 N=3
159: L159F 5 (50%) 1 (33%)
316: C316H 2 (20%) 1 (33%)
        C316N 4 (40%) 1 (33%)
556: S556G 6 (60%) 3 (100%)
Resistance to protease inhibitors N=2 N=1
122: S122N 1 (50%) 1 (100%)
168: D168E 1 (50%) -