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MTDR potently inhibits the mitochondrial oxygen consumption rate (OCR) in MCF7 cells. A representative Seahorse tracing is shown, with bar graphs highlighting the quantitative, dose-dependent effects of MTDR on basal respiration, maximal respiration and ATP production. Note that MTDR treatment exhibits near complete inhibition of OCR in MCF7 cells at 500 nM. The statistical test used was a one-tail unpaired t-test.
