TABLE 1.
Total N = 61 | N (%) |
---|---|
Diagnosis | |
Leukemia, Lymphoma, MDS | 42 (68) |
LCH/HLH | 4 (7) |
Nonmalignant | 15 (25) |
Preparative regimen | |
TBI-based | 23 (38) |
Busulfan-based | 28 (46) |
RIC or Cy/ATG | 10 (16) |
Disease status | |
CRI/untreated | 23 (38) |
CR2 | 11 (18) |
CR3 or refractory | 10 (16) |
Nonmalignant | 17 (28) |
GVHD prophylaxis | |
CNI plus MTX | 48 (79) |
CNI plus CellCept | 9 (15) |
CNI plus steroids | 4 (6) |
HLA | |
10/10 related | 25 (41) |
<10/10 related | 3 (5) |
10/10 unrelated | 21 (34) |
<10/10 unrelated | 12 (20) |
ABO mismatch | |
No mismatch | 36 (59) |
Major mismatch | 13 (21) |
Minor mismatch | 10 (16) |
Bidirectional mismatch | 2 (3) |
Sex mismatch | |
None | 32 (53) |
Female donor, male recipient | 21 (34) |
Male donor, female recipient | 8 (13) |
CMV status | |
Donor (−), recipient (−) | 10 (16) |
Donor (−), recipient (+) | 24 (40) |
Donor (+), recipient (−) | 5 (8) |
Donor (+), recipient (+) | 22 (36) |
GVHD | |
Acute | 18 (30) |
Chronic | 8 (13) |